Cytochrome c oxidase (COX) catalyzes the transfer of electrons from cytochrome c to molecular oxygen, which helps to maintain the proton gradient across the inner mitochondrial membrane that is necessary for aerobic ATP production. Human COX is a multimeric protein complex that requires several assembly factors; this gene encodes one of the COX assembly factors. The encoded protein is a metallochaperone that is involved in the biogenesis of cytochrome c oxidase subunit II. Mutations in this gene are associated with fatal infantile encephalocardiomyopathy and myopia 6. [provided by RefSeq, Oct 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SCO2-20-RE | 20 (40 μL) | 200 μL |  |
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| SCO2-20-OR | 20 (40 μL) | 200 μL |  |
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| SCO2-20-GO | 20 (40 μL) | 200 μL |  |
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| SCO2-20-GR | 20 (40 μL) | 200 μL |  |
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| SCO2-20-AQ | 20 (40 μL) | 200 μL |  |
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Cytochrome c oxidase (COX) catalyzes the transfer of electrons from cytochrome c to molecular oxygen, which helps to maintain the proton gradient across the inner mitochondrial membrane that is necessary for aerobic ATP production. Human COX is a multimeric protein complex that requires several assembly factors; this gene encodes one of the COX assembly factors. The encoded protein is a metallochaperone that is involved in the biogenesis of cytochrome c oxidase subunit II. Mutations in this gene are associated with fatal infantile encephalocardiomyopathy and myopia 6. [provided by RefSeq, Oct 2014]
Gene Symbol : SCO2
Gene Name : SCO2, cytochrome c oxidase assembly protein
Chromosome : CHR 22: 505,264,38-505,235,67
Locus : 22q13.33
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