The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein is thought to be a cargo-binding component of the COPII vesicle, and is thought to be involved in the transport of secretory proteins from the endoplasmic reticulum to the Golgi apparatus. Mutations in this gene have been associated with neural tube defects, and are thought to be a result of a disruption in interactions with the protein encoded by the VANGL planar cell polarity protein 2 (VANGL2) gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SEC24B-20-RE | 20 (40 μL) | 200 μL |  |
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| SEC24B-20-OR | 20 (40 μL) | 200 μL |  |
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| SEC24B-20-GO | 20 (40 μL) | 200 μL |  |
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| SEC24B-20-GR | 20 (40 μL) | 200 μL |  |
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| SEC24B-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein is thought to be a cargo-binding component of the COPII vesicle, and is thought to be involved in the transport of secretory proteins from the endoplasmic reticulum to the Golgi apparatus. Mutations in this gene have been associated with neural tube defects, and are thought to be a result of a disruption in interactions with the protein encoded by the VANGL planar cell polarity protein 2 (VANGL2) gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
Gene Symbol : SEC24B
Gene Name : SEC24 homolog B, COPII coat complex component
Chromosome : CHR 4: 109,433,714-109,540,458
Locus : 4q25
Alt. Genes : RBM12
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