The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SEC61B-20-RE | 20 (40 μL) | 200 μL |  |
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| SEC61B-20-OR | 20 (40 μL) | 200 μL |  |
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| SEC61B-20-GO | 20 (40 μL) | 200 μL |  |
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| SEC61B-20-GR | 20 (40 μL) | 200 μL |  |
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| SEC61B-20-AQ | 20 (40 μL) | 200 μL |  |
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The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript. [provided by RefSeq, Jul 2008]
Gene Symbol : SEC61B
Gene Name : Sec61 translocon beta subunit
Chromosome : CHR 9: 992,222,87-992,306,18
Locus : 9q22.33
Alt. Genes : FEM1B
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