This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SELL-20-RE | 20 (40 μL) | 200 μL |  |
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| SELL-20-OR | 20 (40 μL) | 200 μL |  |
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| SELL-20-GO | 20 (40 μL) | 200 μL |  |
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| SELL-20-GR | 20 (40 μL) | 200 μL |  |
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| SELL-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]
Gene Symbol : SELL
Gene Name : Selectin L
Chromosome : CHR 1: 169,711,701-169,690,664
Locus : 1q24.2
Alt. Genes : HIPK3
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