This gene encodes a member of the semaphorin family of proteins. The encoded preproprotein is proteolytically processed to generate the mature glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein. The encoded protein is found on activated lymphocytes and erythrocytes and may be involved in immunomodulatory and neuronal processes. The encoded protein carries the John Milton Hagen (JMH) blood group antigens. Mutations in this gene may be associated with reduced bone mineral density (BMD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
SEMA7A-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
SEMA7A-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
SEMA7A-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
SEMA7A-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
SEMA7A-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes a member of the semaphorin family of proteins. The encoded preproprotein is proteolytically processed to generate the mature glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein. The encoded protein is found on activated lymphocytes and erythrocytes and may be involved in immunomodulatory and neuronal processes. The encoded protein carries the John Milton Hagen (JMH) blood group antigens. Mutations in this gene may be associated with reduced bone mineral density (BMD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
Gene Symbol : SEMA7A
Gene Name : Semaphorin 7A (John Milton Hagen blood group)
Chromosome : CHR 15: 744,339,58-744,092,83
Locus : 15q24.1
Alt. Genes : LRPPRC
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