The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP3, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).[supplied by OMIM, Jun 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SENP3-20-RE | 20 (40 μL) | 200 μL |  |
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| SENP3-20-OR | 20 (40 μL) | 200 μL |  |
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| SENP3-20-GO | 20 (40 μL) | 200 μL |  |
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| SENP3-20-GR | 20 (40 μL) | 200 μL |  |
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| SENP3-20-AQ | 20 (40 μL) | 200 μL |  |
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The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP3, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).[supplied by OMIM, Jun 2009]
Gene Symbol : SENP3
Gene Name : SUMO1/sentrin/SMT3 specific peptidase 3
Chromosome : CHR 17: 756,199,1-757,196,8
Locus : 17p13.1
Alt. Genes : CEBPZ
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