The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).[supplied by OMIM, Jun 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SENP7-20-RE | 20 (40 μL) | 200 μL |  |
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| SENP7-20-OR | 20 (40 μL) | 200 μL |  |
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| SENP7-20-GO | 20 (40 μL) | 200 μL |  |
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| SENP7-20-GR | 20 (40 μL) | 200 μL |  |
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| SENP7-20-AQ | 20 (40 μL) | 200 μL |  |
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The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).[supplied by OMIM, Jun 2009]
Gene Symbol : SENP7
Gene Name : SUMO1/sentrin specific peptidase 7
Chromosome : CHR 3: 101,513,240-101,324,188
Locus : 3q12.3
Alt. Genes : OPTN
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