This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SERPING1-20-RE | 20 (40 μL) | 200 μL |  |
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| SERPING1-20-OR | 20 (40 μL) | 200 μL |  |
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| SERPING1-20-GO | 20 (40 μL) | 200 μL |  |
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| SERPING1-20-GR | 20 (40 μL) | 200 μL |  |
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| SERPING1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform. [provided by RefSeq, Jul 2008]
Gene Symbol : SERPING1
Gene Name : Serpin family G member 1
Chromosome : CHR 11: 575,975,53-576,148,52
Locus : 11q12.1
Alt. Genes : OPTN
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