This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SESN3-20-RE | 20 (40 μL) | 200 μL |  |
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| SESN3-20-OR | 20 (40 μL) | 200 μL |  |
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| SESN3-20-GO | 20 (40 μL) | 200 μL |  |
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| SESN3-20-GR | 20 (40 μL) | 200 μL |  |
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| SESN3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]
Gene Symbol : SESN3
Gene Name : Sestrin 3
Chromosome : CHR 11: 952,325,40-951,655,12
Locus : 11q21
Alt. Genes : OPTN
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