Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SETD2-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| SETD2-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| SETD2-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| SETD2-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| SETD2-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]
Gene Symbol : SETD2
Gene Name : SET domain containing 2
Chromosome : CHR 3: 471,641,08-470,164,07
Locus : 3p21.31
Alt. Genes : FEM1B
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.