This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.[provided by RefSeq, Jun 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SETDB1-20-RE | 20 (40 μL) | 200 μL |  |
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| SETDB1-20-OR | 20 (40 μL) | 200 μL |  |
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| SETDB1-20-GO | 20 (40 μL) | 200 μL |  |
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| SETDB1-20-GR | 20 (40 μL) | 200 μL |  |
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| SETDB1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.[provided by RefSeq, Jun 2011]
Gene Symbol : SETDB1
Gene Name : SET domain bifurcated 1
Chromosome : CHR 1: 150,926,245-150,964,743
Locus : 1q21.3
Alt. Genes : HIPK3
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