This gene encodes a member of a family of proteins that contain a methyl-CpG-binding domain (MBD) and a SET domain and function as histone methyltransferases. This protein is recruited to heterochromatin and plays a role in the regulation of chromosome segregation. This region is commonly deleted in chronic lymphocytic leukemia. Naturally-occuring readthrough transcription occurs from this gene to the downstream PHF11 (PHD finger protein 11) gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SETDB2-20-RE | 20 (40 μL) | 200 μL |  |
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| SETDB2-20-OR | 20 (40 μL) | 200 μL |  |
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| SETDB2-20-GO | 20 (40 μL) | 200 μL |  |
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| SETDB2-20-GR | 20 (40 μL) | 200 μL |  |
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| SETDB2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of a family of proteins that contain a methyl-CpG-binding domain (MBD) and a SET domain and function as histone methyltransferases. This protein is recruited to heterochromatin and plays a role in the regulation of chromosome segregation. This region is commonly deleted in chronic lymphocytic leukemia. Naturally-occuring readthrough transcription occurs from this gene to the downstream PHF11 (PHD finger protein 11) gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Gene Symbol : SETDB2
Gene Name : SET domain bifurcated 2
Chromosome : CHR 13: 494,442,92-494,950,02
Locus : 13q14.2
Alt. Genes : PLXNC1
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