This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C). [provided by RefSeq, Oct 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SGCG-20-RE | 20 (40 μL) | 200 μL |  |
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| SGCG-20-OR | 20 (40 μL) | 200 μL |  |
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| SGCG-20-GO | 20 (40 μL) | 200 μL |  |
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| SGCG-20-GR | 20 (40 μL) | 200 μL |  |
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| SGCG-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C). [provided by RefSeq, Oct 2008]
Gene Symbol : SGCG
Gene Name : Sarcoglycan gamma
Chromosome : CHR 13: 231,603,07-233,251,64
Locus : 13q12.12
Alt. Genes : LRPPRC
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