This gene encodes a member of the endophilin family of Src homology 3 domain-containing proteins. The encoded protein is involved in endocytosis and may also play a role in the cell cycle. Overexpression of this gene may play a role in leukemogenesis, and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein. Pseudogenes of this gene are located on the long arm of chromosomes 11 and 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SH3GL1-20-RE | 20 (40 μL) | 200 μL |  |
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| SH3GL1-20-OR | 20 (40 μL) | 200 μL |  |
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| SH3GL1-20-GO | 20 (40 μL) | 200 μL |  |
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| SH3GL1-20-GR | 20 (40 μL) | 200 μL |  |
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| SH3GL1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the endophilin family of Src homology 3 domain-containing proteins. The encoded protein is involved in endocytosis and may also play a role in the cell cycle. Overexpression of this gene may play a role in leukemogenesis, and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein. Pseudogenes of this gene are located on the long arm of chromosomes 11 and 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Gene Symbol : SH3GL1
Gene Name : SH3 domain containing GRB2 like 1, endophilin A2
Chromosome : CHR 19: 440,056,7-436,036,6
Locus : 19p13.3
Alt. Genes : AKAP9
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