This gene encodes an adapter protein that is characterized by a PX domain and four Src homology 3 domains. The encoded protein is required for podosome formation and is involved in cell adhesion and migration of numerous cell types. Mutations in this gene are the cause of Frank-ter Haar syndrome (FTHS), and also Borrone Dermato-Cardio-Skeletal (BDCS) syndrome. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SH3PXD2B-20-RE | 20 (40 μL) | 200 μL |  |
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| SH3PXD2B-20-OR | 20 (40 μL) | 200 μL |  |
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| SH3PXD2B-20-GO | 20 (40 μL) | 200 μL |  |
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| SH3PXD2B-20-GR | 20 (40 μL) | 200 μL |  |
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| SH3PXD2B-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes an adapter protein that is characterized by a PX domain and four Src homology 3 domains. The encoded protein is required for podosome formation and is involved in cell adhesion and migration of numerous cell types. Mutations in this gene are the cause of Frank-ter Haar syndrome (FTHS), and also Borrone Dermato-Cardio-Skeletal (BDCS) syndrome. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Gene Symbol : SH3PXD2B
Gene Name : SH3 and PX domains 2B
Chromosome : CHR 5: 172,454,522-172,325,180
Locus : 5q35.1
Alt. Genes : FEM1B
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