This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SHMT2-20-RE | 20 (40 μL) | 200 μL |  |
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| SHMT2-20-OR | 20 (40 μL) | 200 μL |  |
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| SHMT2-20-GO | 20 (40 μL) | 200 μL |  |
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| SHMT2-20-GR | 20 (40 μL) | 200 μL |  |
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| SHMT2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Gene Symbol : SHMT2
Gene Name : Serine hydroxymethyltransferase 2
Chromosome : CHR 12: 572,295,72-572,349,34
Locus : 12q13.3
Alt. Genes : FAM13A
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