This gene represents the human homolog of Xenopus laevis apical protein (APX) gene, which is implicated in amiloride-sensitive sodium channel activity. It is expressed in endothelial cells and facilitates the formation of a contractile network within endothelial cells. Depletion of this gene results in an increase in endothelial sprouting, migration, and angiogenesis. This gene is highly expressed in the retina, and is a strong candidate for ocular albinism type 1 syndrome. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SHROOM2-20-RE | 20 (40 μL) | 200 μL |  |
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| SHROOM2-20-OR | 20 (40 μL) | 200 μL |  |
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| SHROOM2-20-GO | 20 (40 μL) | 200 μL |  |
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| SHROOM2-20-GR | 20 (40 μL) | 200 μL |  |
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| SHROOM2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene represents the human homolog of Xenopus laevis apical protein (APX) gene, which is implicated in amiloride-sensitive sodium channel activity. It is expressed in endothelial cells and facilitates the formation of a contractile network within endothelial cells. Depletion of this gene results in an increase in endothelial sprouting, migration, and angiogenesis. This gene is highly expressed in the retina, and is a strong candidate for ocular albinism type 1 syndrome. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016]
Gene Symbol : SHROOM2
Gene Name : Shroom family member 2
Chromosome : CHR X: 978,640,5-994,944,2
Locus : Xp22.2
Alt. Genes : OPTN
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