The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SIPA1-20-RE | 20 (40 μL) | 200 μL |  |
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| SIPA1-20-OR | 20 (40 μL) | 200 μL |  |
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| SIPA1-20-GO | 20 (40 μL) | 200 μL |  |
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| SIPA1-20-GR | 20 (40 μL) | 200 μL |  |
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| SIPA1-20-AQ | 20 (40 μL) | 200 μL |  |
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The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date. [provided by RefSeq, Jul 2008]
Gene Symbol : SIPA1
Gene Name : Signal-induced proliferation-associated 1
Chromosome : CHR 11: 656,381,06-656,509,29
Locus : 11q13.1
Alt. Genes : CEBPZ
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