The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SIRPB1-20-RE | 20 (40 μL) | 200 μL |  |
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| SIRPB1-20-OR | 20 (40 μL) | 200 μL |  |
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| SIRPB1-20-GO | 20 (40 μL) | 200 μL |  |
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| SIRPB1-20-GR | 20 (40 μL) | 200 μL |  |
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| SIRPB1-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]
Gene Symbol : SIRPB1
Gene Name : Signal regulatory protein beta 1
Chromosome : CHR 20: 162,045,6-156,419,2
Locus : 20p13
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