This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. [provided by RefSeq, Jul 2008]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
SIRT4-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
SIRT4-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
SIRT4-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
SIRT4-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
SIRT4-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. [provided by RefSeq, Jul 2008]
Gene Symbol : SIRT4
Gene Name : Sirtuin 4
Chromosome : CHR 12: 120,292,198-120,313,241
Locus : 12q24.23-q24.31
Alt. Genes : LRPPRC
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