This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SIRT6-20-RE | 20 (40 μL) | 200 μL |  |
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| SIRT6-20-OR | 20 (40 μL) | 200 μL |  |
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| SIRT6-20-GO | 20 (40 μL) | 200 μL |  |
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| SIRT6-20-GR | 20 (40 μL) | 200 μL |  |
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| SIRT6-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]
Gene Symbol : SIRT6
Gene Name : Sirtuin 6
Chromosome : CHR 19: 418,260,3-417,410,8
Locus : 19p13.3
Alt. Genes : OPTN
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