This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SKAP1-20-RE | 20 (40 μL) | 200 μL |  |
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| SKAP1-20-OR | 20 (40 μL) | 200 μL |  |
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| SKAP1-20-GO | 20 (40 μL) | 200 μL |  |
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| SKAP1-20-GR | 20 (40 μL) | 200 μL |  |
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| SKAP1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins. [provided by RefSeq, Jul 2008]
Gene Symbol : SKAP1
Gene Name : Src kinase associated phosphoprotein 1
Chromosome : CHR 17: 484,302,90-481,334,37
Locus : 17q21.32
Alt. Genes : TRAP1
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