K-Cl cotransporters are proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The protein encoded by this gene is an integral membrane K-Cl cotransporter that can function in either a net efflux or influx pathway, depending on the chemical concentration gradients of potassium and chloride. The encoded protein can act as a homomultimer, or as a heteromultimer with other K-Cl cotransporters, to maintain chloride homeostasis in neurons. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Sep 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SLC12A5-20-RE | 20 (40 μL) | 200 μL |  |
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| SLC12A5-20-OR | 20 (40 μL) | 200 μL |  |
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| SLC12A5-20-GO | 20 (40 μL) | 200 μL |  |
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| SLC12A5-20-GR | 20 (40 μL) | 200 μL |  |
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| SLC12A5-20-AQ | 20 (40 μL) | 200 μL |  |
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K-Cl cotransporters are proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The protein encoded by this gene is an integral membrane K-Cl cotransporter that can function in either a net efflux or influx pathway, depending on the chemical concentration gradients of potassium and chloride. The encoded protein can act as a homomultimer, or as a heteromultimer with other K-Cl cotransporters, to maintain chloride homeostasis in neurons. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Sep 2008]
Gene Symbol : SLC12A5
Gene Name : Solute carrier family 12 member 5
Chromosome : CHR 20: 460,216,89-460,601,49
Locus : 20q13.12
Alt. Genes : YAF2
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