Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]).[supplied by OMIM, Mar 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SLC16A3-20-RE | 20 (40 μL) | 200 μL |  |
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| SLC16A3-20-OR | 20 (40 μL) | 200 μL |  |
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| SLC16A3-20-GO | 20 (40 μL) | 200 μL |  |
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| SLC16A3-20-GR | 20 (40 μL) | 200 μL |  |
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| SLC16A3-20-AQ | 20 (40 μL) | 200 μL |  |
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Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]).[supplied by OMIM, Mar 2008]
Gene Symbol : SLC16A3
Gene Name : Solute carrier family 16 member 3
Chromosome : CHR 17: 822,284,05-822,394,98
Locus : 17q25.3
Alt. Genes : RBM12
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