The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (Peter et al., 1993 [PubMed 7905859]). See also SLC18A2 (MIM 193001).[supplied by OMIM, Mar 2008]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
SLC18A1-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
SLC18A1-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
SLC18A1-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
SLC18A1-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
SLC18A1-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (Peter et al., 1993 [PubMed 7905859]). See also SLC18A2 (MIM 193001).[supplied by OMIM, Mar 2008]
Gene Symbol : SLC18A1
Gene Name : Solute carrier family 18 member A1
Chromosome : CHR 8: 201,832,05-201,448,54
Locus : 8p21.3
Alt. Genes : RBM12
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