The vesicular monoamine transporter acts to accumulate cytosolic monoamines into synaptic vesicles, using the proton gradient maintained across the synaptic vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (summary by Peter et al., 1993 [PubMed 7905859]). See also SLC18A1 (MIM 193002).[supplied by OMIM, Jan 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SLC18A2-20-RE | 20 (40 μL) | 200 μL |  |
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| SLC18A2-20-OR | 20 (40 μL) | 200 μL |  |
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| SLC18A2-20-GO | 20 (40 μL) | 200 μL |  |
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| SLC18A2-20-GR | 20 (40 μL) | 200 μL |  |
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| SLC18A2-20-AQ | 20 (40 μL) | 200 μL |  |
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The vesicular monoamine transporter acts to accumulate cytosolic monoamines into synaptic vesicles, using the proton gradient maintained across the synaptic vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (summary by Peter et al., 1993 [PubMed 7905859]). See also SLC18A1 (MIM 193002).[supplied by OMIM, Jan 2011]
Gene Symbol : SLC18A2
Gene Name : Solute carrier family 18 member A2
Chromosome : CHR 10: 117,241,072-117,279,429
Locus : 10q25.3
Alt. Genes : OPTN
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