This gene encodes a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. In brain, these transporters are crucial in terminating the postsynaptic action of the neurotransmitter glutamate, and in maintaining extracellular glutamate concentrations below neurotoxic levels. This transporter also transports aspartate, and mutations in this gene are thought to cause dicarboxylicamino aciduria, also known as glutamate-aspartate transport defect. [provided by RefSeq, Mar 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SLC1A1-20-RE | 20 (40 μL) | 200 μL |  |
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| SLC1A1-20-OR | 20 (40 μL) | 200 μL |  |
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| SLC1A1-20-GO | 20 (40 μL) | 200 μL |  |
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| SLC1A1-20-GR | 20 (40 μL) | 200 μL |  |
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| SLC1A1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. In brain, these transporters are crucial in terminating the postsynaptic action of the neurotransmitter glutamate, and in maintaining extracellular glutamate concentrations below neurotoxic levels. This transporter also transports aspartate, and mutations in this gene are thought to cause dicarboxylicamino aciduria, also known as glutamate-aspartate transport defect. [provided by RefSeq, Mar 2010]
Gene Symbol : SLC1A1
Gene Name : Solute carrier family 1 member 1
Chromosome : CHR 9: 449,042,6-458,746,8
Locus : 9p24.2
Alt. Genes : TRAP1
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