The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SLC22A12-20-RE | 20 (40 μL) | 200 μL |  |
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| SLC22A12-20-OR | 20 (40 μL) | 200 μL |  |
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| SLC22A12-20-GO | 20 (40 μL) | 200 μL |  |
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| SLC22A12-20-GR | 20 (40 μL) | 200 μL |  |
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| SLC22A12-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
Gene Symbol : SLC22A12
Gene Name : Solute carrier family 22 member 12
Chromosome : CHR 11: 645,908,09-646,032,49
Locus : 11q13.1
Alt. Genes : ZNF197
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