The protein encoded by this gene is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
SLC30A8-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
SLC30A8-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
SLC30A8-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
SLC30A8-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
SLC30A8-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
The protein encoded by this gene is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010]
Gene Symbol : SLC30A8
Gene Name : Solute carrier family 30 member 8
Chromosome : CHR 8: 116,950,272-117,176,713
Locus : 8q24.11
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