Normal blood lactate is maintained at about 1.5 mM, and little filtered lactate is excreted in urine. Reabsorption of lactate is mediated by the low-affinity Na(+)-coupled lactate transporter SLC5A12 in the initial part of the proximal tubule and by the high-affinity Na(+)-coupled lactate transporter SLC5A8 (MIM 608044) in the distal proximal tubule (Gopal et al., 2007 [PubMed 17692818]).[supplied by OMIM, Dec 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SLC5A12-20-RE | 20 (40 μL) | 200 μL |  |
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| SLC5A12-20-OR | 20 (40 μL) | 200 μL |  |
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| SLC5A12-20-GO | 20 (40 μL) | 200 μL |  |
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| SLC5A12-20-GR | 20 (40 μL) | 200 μL |  |
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| SLC5A12-20-AQ | 20 (40 μL) | 200 μL |  |
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Normal blood lactate is maintained at about 1.5 mM, and little filtered lactate is excreted in urine. Reabsorption of lactate is mediated by the low-affinity Na(+)-coupled lactate transporter SLC5A12 in the initial part of the proximal tubule and by the high-affinity Na(+)-coupled lactate transporter SLC5A8 (MIM 608044) in the distal proximal tubule (Gopal et al., 2007 [PubMed 17692818]).[supplied by OMIM, Dec 2008]
Gene Symbol : SLC5A12
Gene Name : Solute carrier family 5 member 12
Chromosome : CHR 11: 267,233,55-266,670,18
Locus : 11p14.2
Alt. Genes : LRPPRC
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