This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SLC6A4-20-RE | 20 (40 μL) | 200 μL |  |
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| SLC6A4-20-OR | 20 (40 μL) | 200 μL |  |
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| SLC6A4-20-GO | 20 (40 μL) | 200 μL |  |
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| SLC6A4-20-GR | 20 (40 μL) | 200 μL |  |
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| SLC6A4-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq, Jul 2008]
Gene Symbol : SLC6A4
Gene Name : Solute carrier family 6 member 4
Chromosome : CHR 17: 302,359,67-301,943,18
Locus : 17q11.2
Alt. Genes : ENAM
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