This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of endogenous and xenobiotic compounds and plays a critical role in bile acid and bilirubin transport. Mutations in this gene are a cause of Rotor type hyperbilirubinemia. Alternative splicing of this gene and the use of alternative promoters results in transcript variants encoding different isoforms that differ in their tissue specificity. [provided by RefSeq, Mar 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SLCO1B3-20-RE | 20 (40 μL) | 200 μL |  |
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| SLCO1B3-20-OR | 20 (40 μL) | 200 μL |  |
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| SLCO1B3-20-GO | 20 (40 μL) | 200 μL |  |
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| SLCO1B3-20-GR | 20 (40 μL) | 200 μL |  |
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| SLCO1B3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of endogenous and xenobiotic compounds and plays a critical role in bile acid and bilirubin transport. Mutations in this gene are a cause of Rotor type hyperbilirubinemia. Alternative splicing of this gene and the use of alternative promoters results in transcript variants encoding different isoforms that differ in their tissue specificity. [provided by RefSeq, Mar 2017]
Gene Symbol : SLCO1B3
Gene Name : Solute carrier organic anion transporter family member 1B3
Chromosome : CHR 12: 208,107,03-209,169,10
Locus : 12p12.2
Alt. Genes : TRAIP
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