This gene encodes a novel, secreted member of the Ly6/uPAR (LU) superfamily of proteins containing the unique three-finger LU domain. This gene is mainly expressed in epithelial cells, including skin and keratinocytes, and is up-regulated in psoriatic skin lesions, suggesting its involvement in the pathophysiology of psoriasis. Alternatively spliced transcript variants have been found for this gene. Read-through transcription from the neighboring upstream gene (LYNX1) generates naturally-occurring transcripts (LYNX1-SLURP2) that encode a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Sep 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SLURP2-20-RE | 20 (40 μL) | 200 μL |  |
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| SLURP2-20-OR | 20 (40 μL) | 200 μL |  |
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| SLURP2-20-GO | 20 (40 μL) | 200 μL |  |
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| SLURP2-20-GR | 20 (40 μL) | 200 μL |  |
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| SLURP2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a novel, secreted member of the Ly6/uPAR (LU) superfamily of proteins containing the unique three-finger LU domain. This gene is mainly expressed in epithelial cells, including skin and keratinocytes, and is up-regulated in psoriatic skin lesions, suggesting its involvement in the pathophysiology of psoriasis. Alternatively spliced transcript variants have been found for this gene. Read-through transcription from the neighboring upstream gene (LYNX1) generates naturally-occurring transcripts (LYNX1-SLURP2) that encode a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Sep 2017]
Gene Symbol : SLURP2
Gene Name : Secreted LY6/PLAUR domain containing 2
Chromosome : CHR 8: 0-0
Locus : 8q24.3
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