This gene encodes a protein that is an important regulator of genome stability. The protein represents the catalytic subunit of the SLX1-SLX4 structure-specific endonuclease, which can resolve DNA secondary structures that are formed during repair and recombination processes. Two identical copies of this gene are located on the p arm of chromosome 16 due to a segmental duplication; this record represents the more centromeric copy. Alternative splicing results in multiple transcript variants. Read-through transcription also occurs between this gene and the downstream SULT1A3 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3) gene. [provided by RefSeq, Nov 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SLX1A-20-RE | 20 (40 μL) | 200 μL |  |
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| SLX1A-20-OR | 20 (40 μL) | 200 μL |  |
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| SLX1A-20-GO | 20 (40 μL) | 200 μL |  |
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| SLX1A-20-GR | 20 (40 μL) | 200 μL |  |
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| SLX1A-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein that is an important regulator of genome stability. The protein represents the catalytic subunit of the SLX1-SLX4 structure-specific endonuclease, which can resolve DNA secondary structures that are formed during repair and recombination processes. Two identical copies of this gene are located on the p arm of chromosome 16 due to a segmental duplication; this record represents the more centromeric copy. Alternative splicing results in multiple transcript variants. Read-through transcription also occurs between this gene and the downstream SULT1A3 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3) gene. [provided by RefSeq, Nov 2010]
Gene Symbol : SLX1A
Gene Name : SLX1 homolog A, structure-specific endonuclease subunit
Chromosome : CHR 16: 301,938,42-301,975,65
Locus : 16p11.2
Alt. Genes : CEBPZ
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