The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SMARCB1-20-RE | 20 (40 μL) | 200 μL |  |
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| SMARCB1-20-OR | 20 (40 μL) | 200 μL |  |
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| SMARCB1-20-GO | 20 (40 μL) | 200 μL |  |
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| SMARCB1-20-GR | 20 (40 μL) | 200 μL |  |
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| SMARCB1-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2015]
Gene Symbol : SMARCB1
Gene Name : SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
Chromosome : CHR 22: 237,869,30-238,345,17
Locus : 22q11
Alt. Genes : RBM12
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