This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SMC3-20-RE | 20 (40 μL) | 200 μL |  |
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| SMC3-20-OR | 20 (40 μL) | 200 μL |  |
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| SMC3-20-GO | 20 (40 μL) | 200 μL |  |
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| SMC3-20-GR | 20 (40 μL) | 200 μL |  |
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| SMC3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein. [provided by RefSeq, Jul 2008]
Gene Symbol : SMC3
Gene Name : Structural maintenance of chromosomes 3
Chromosome : CHR 10: 110,567,690-110,604,633
Locus : 10q25.2
Alt. Genes : ARPC2
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