This gene encodes a component of the telomerase ribonucleoprotein complex responsible for the replication and maintenance of chromosome ends. The encoded protein also plays a role in the nonsense-mediated mRNA decay (NMD) pathway, providing the endonuclease activity near the premature translation termination codon that is needed to initiate NMD. Alternatively spliced transcript variants encoding distinct protein isoforms have been described. [provided by RefSeq, Feb 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SMG6-20-RE | 20 (40 μL) | 200 μL |  |
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| SMG6-20-OR | 20 (40 μL) | 200 μL |  |
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| SMG6-20-GO | 20 (40 μL) | 200 μL |  |
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| SMG6-20-GR | 20 (40 μL) | 200 μL |  |
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| SMG6-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a component of the telomerase ribonucleoprotein complex responsible for the replication and maintenance of chromosome ends. The encoded protein also plays a role in the nonsense-mediated mRNA decay (NMD) pathway, providing the endonuclease activity near the premature translation termination codon that is needed to initiate NMD. Alternatively spliced transcript variants encoding distinct protein isoforms have been described. [provided by RefSeq, Feb 2014]
Gene Symbol : SMG6
Gene Name : SMG6, nonsense mediated mRNA decay factor
Chromosome : CHR 17: 230,383,5-205,983,8
Locus : 17p13.3
Alt. Genes : PREB
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