This gene encodes a regulatory subunit of the SMG1 complex, which plays a critical role in nonsense-mediated mRNA decay (NMD). Binding of the encoded protein to the SMG1 complex kinase scaffold protein results in the inhibition of its kinase activity. Mutations in this gene cause a multiple congenital anomaly syndrome in human patients, characterized by brain malformation, congenital heart disease and other features. [provided by RefSeq, Jul 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SMG9-20-RE | 20 (40 μL) | 200 μL |  |
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| SMG9-20-OR | 20 (40 μL) | 200 μL |  |
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| SMG9-20-GO | 20 (40 μL) | 200 μL |  |
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| SMG9-20-GR | 20 (40 μL) | 200 μL |  |
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| SMG9-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a regulatory subunit of the SMG1 complex, which plays a critical role in nonsense-mediated mRNA decay (NMD). Binding of the encoded protein to the SMG1 complex kinase scaffold protein results in the inhibition of its kinase activity. Mutations in this gene cause a multiple congenital anomaly syndrome in human patients, characterized by brain malformation, congenital heart disease and other features. [provided by RefSeq, Jul 2016]
Gene Symbol : SMG9
Gene Name : SMG9, nonsense mediated mRNA decay factor
Chromosome : CHR 19: 437,549,89-437,279,91
Locus : 19q13.31
Alt. Genes : TRAP1
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