This gene encodes a member of the SPARC family (secreted protein acidic and rich in cysteine/osteonectin/BM-40), which are highly expressed during embryogenesis and wound healing. The gene product is a matricellular protein which promotes matrix assembly and can stimulate endothelial cell proliferation and migration, as well as angiogenic activity. Associated with pulmonary function, this secretory gene product contains a Kazal domain, two thymoglobulin type-1 domains, and two EF-hand calcium-binding domains. The encoded protein may serve as a target for controlling angiogenesis in tumor growth and myocardial ischemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SMOC2-20-RE | 20 (40 μL) | 200 μL |  |
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| SMOC2-20-OR | 20 (40 μL) | 200 μL |  |
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| SMOC2-20-GO | 20 (40 μL) | 200 μL |  |
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| SMOC2-20-GR | 20 (40 μL) | 200 μL |  |
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| SMOC2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the SPARC family (secreted protein acidic and rich in cysteine/osteonectin/BM-40), which are highly expressed during embryogenesis and wound healing. The gene product is a matricellular protein which promotes matrix assembly and can stimulate endothelial cell proliferation and migration, as well as angiogenic activity. Associated with pulmonary function, this secretory gene product contains a Kazal domain, two thymoglobulin type-1 domains, and two EF-hand calcium-binding domains. The encoded protein may serve as a target for controlling angiogenesis in tumor growth and myocardial ischemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Gene Symbol : SMOC2
Gene Name : SPARC related modular calcium binding 2
Chromosome : CHR 6: 168,441,150-168,667,993
Locus : 6q27
Alt. Genes : ZNF263
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