The protein encoded by this gene is a component of the endosomal sorting complex required for transport II (ESCRT-II), which regulates the movement of ubiquitinylated transmembrane proteins to the lysosome for degradation. This complex also interacts with the RNA polymerase II elongation factor (ELL) to overcome the repressive effects of ELL on RNA polymerase II activity. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SNF8-20-RE | 20 (40 μL) | 200 μL |  |
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| SNF8-20-OR | 20 (40 μL) | 200 μL |  |
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| SNF8-20-GO | 20 (40 μL) | 200 μL |  |
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| SNF8-20-GR | 20 (40 μL) | 200 μL |  |
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| SNF8-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a component of the endosomal sorting complex required for transport II (ESCRT-II), which regulates the movement of ubiquitinylated transmembrane proteins to the lysosome for degradation. This complex also interacts with the RNA polymerase II elongation factor (ELL) to overcome the repressive effects of ELL on RNA polymerase II activity. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
Gene Symbol : SNF8
Gene Name : SNF8, ESCRT-II complex subunit
Chromosome : CHR 17: 489,448,41-489,300,95
Locus : 17q21.32
Alt. Genes : LRPPRC
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