This gene encodes a protein that contains a coiled-coil motif and C-terminal forkhead-associated (FHA) domain. The encoded protein functions as a transcriptional coactivator that increases c-Myc activity and inhibits transforming growth factor beta (TGF-beta) and nuclear factor kappa-B (NF-kB) signaling. The encoded protein also regulates the stability of cyclin D1 mRNA, and may play a role in cell proliferation and cancer progression. Mutations in this gene are a cause of psychomotor retardation, epilepsy, and craniofacial dysmorphism (PMRED). [provided by RefSeq, Mar 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SNIP1-20-RE | 20 (40 μL) | 200 μL |  |
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| SNIP1-20-OR | 20 (40 μL) | 200 μL |  |
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| SNIP1-20-GO | 20 (40 μL) | 200 μL |  |
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| SNIP1-20-GR | 20 (40 μL) | 200 μL |  |
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| SNIP1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein that contains a coiled-coil motif and C-terminal forkhead-associated (FHA) domain. The encoded protein functions as a transcriptional coactivator that increases c-Myc activity and inhibits transforming growth factor beta (TGF-beta) and nuclear factor kappa-B (NF-kB) signaling. The encoded protein also regulates the stability of cyclin D1 mRNA, and may play a role in cell proliferation and cancer progression. Mutations in this gene are a cause of psychomotor retardation, epilepsy, and craniofacial dysmorphism (PMRED). [provided by RefSeq, Mar 2012]
Gene Symbol : SNIP1
Gene Name : Smad nuclear interacting protein 1
Chromosome : CHR 1: 375,543,43-375,344,48
Locus : 1p34.3
Alt. Genes : ENAM
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