Islet antigen-2 (IA-2) is an autoantigen in type 1 diabetes and plays a role in insulin secretion. IA-2 is found in dense-core secretory vesicles and interacts with the product of this gene, a sorting nexin. In mouse pancreatic beta-cells, the encoded protein influenced insulin secretion by stabilizing the number of dense-core secretory vesicles. [provided by RefSeq, Dec 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SNX19-20-RE | 20 (40 μL) | 200 μL |  |
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| SNX19-20-OR | 20 (40 μL) | 200 μL |  |
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| SNX19-20-GO | 20 (40 μL) | 200 μL |  |
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| SNX19-20-GR | 20 (40 μL) | 200 μL |  |
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| SNX19-20-AQ | 20 (40 μL) | 200 μL |  |
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Islet antigen-2 (IA-2) is an autoantigen in type 1 diabetes and plays a role in insulin secretion. IA-2 is found in dense-core secretory vesicles and interacts with the product of this gene, a sorting nexin. In mouse pancreatic beta-cells, the encoded protein influenced insulin secretion by stabilizing the number of dense-core secretory vesicles. [provided by RefSeq, Dec 2016]
Gene Symbol : SNX19
Gene Name : Sorting nexin 19
Chromosome : CHR 11: 130,916,487-130,866,253
Locus : 11q24.3-q25
Alt. Genes : KIF20A
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