The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SOCS6-20-RE | 20 (40 μL) | 200 μL |  |
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| SOCS6-20-OR | 20 (40 μL) | 200 μL |  |
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| SOCS6-20-GO | 20 (40 μL) | 200 μL |  |
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| SOCS6-20-GR | 20 (40 μL) | 200 μL |  |
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| SOCS6-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines. [provided by RefSeq, Jul 2008]
Gene Symbol : SOCS6
Gene Name : Suppressor of cytokine signaling 6
Chromosome : CHR 18: 702,889,00-703,301,98
Locus : 18q22.2
Alt. Genes : TSPAN3
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