This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. [provided by RefSeq, Apr 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SOD2-20-RE | 20 (40 μL) | 200 μL |  |
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| SOD2-20-OR | 20 (40 μL) | 200 μL |  |
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| SOD2-20-GO | 20 (40 μL) | 200 μL |  |
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| SOD2-20-GR | 20 (40 μL) | 200 μL |  |
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| SOD2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. [provided by RefSeq, Apr 2016]
Gene Symbol : SOD2
Gene Name : Superoxide dismutase 2
Chromosome : CHR 6: 159,762,528-159,679,063
Locus : 6q25.3
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