This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SOS1-20-RE | 20 (40 μL) | 200 μL |  |
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| SOS1-20-OR | 20 (40 μL) | 200 μL |  |
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| SOS1-20-GO | 20 (40 μL) | 200 μL |  |
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| SOS1-20-GR | 20 (40 μL) | 200 μL |  |
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| SOS1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq, Jul 2008]
Gene Symbol : SOS1
Gene Name : SOS Ras/Rac guanine nucleotide exchange factor 1
Chromosome : CHR 2: 391,249,58-389,815,48
Locus : 2p22.1
Alt. Genes : RAD50
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