This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the cognitive disability found in an alpha-thalassemia-related syndrome (ART-16). This protein is also highly expressed in the majority of human hepatocellular carcinomas and promotes cellular proliferation and enhanced tumor growth. [provided by RefSeq, Jul 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SOX8-20-RE | 20 (40 μL) | 200 μL |  |
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| SOX8-20-OR | 20 (40 μL) | 200 μL |  |
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| SOX8-20-GO | 20 (40 μL) | 200 μL |  |
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| SOX8-20-GR | 20 (40 μL) | 200 μL |  |
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| SOX8-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the cognitive disability found in an alpha-thalassemia-related syndrome (ART-16). This protein is also highly expressed in the majority of human hepatocellular carcinomas and promotes cellular proliferation and enhanced tumor growth. [provided by RefSeq, Jul 2017]
Gene Symbol : SOX8
Gene Name : SRY-box 8
Chromosome : CHR 16: 981,807-986,978
Locus : 16p13.3
Alt. Genes : FAM13A
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