This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.[provided by RefSeq, Jan 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SPA17-20-RE | 20 (40 μL) | 200 μL |  |
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| SPA17-20-OR | 20 (40 μL) | 200 μL |  |
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| SPA17-20-GO | 20 (40 μL) | 200 μL |  |
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| SPA17-20-GR | 20 (40 μL) | 200 μL |  |
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| SPA17-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.[provided by RefSeq, Jan 2009]
Gene Symbol : SPA17
Gene Name : Sperm autoantigenic protein 17
Chromosome : CHR 11: 124,673,843-124,694,793
Locus : 11q24.2
Alt. Genes : CEBPZ
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