The protein encoded by this gene is a Kazal-type serine protease inhibitor that appears to specifically target kallikrein-related peptidase 5 (KLK5) in the palmo-plantar epidermis. KLK5 is an important initiator of skin desquamation, so the encoded protease inhibitor may regulate skin differentiation in the palms of hands and soles of feet. This cationic protein has also been shown to promote keratinocyte migration by activation of the epidermal growth factor receptor (EGFR). [provided by RefSeq, Dec 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SPINK9-20-RE | 20 (40 μL) | 200 μL |  |
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| SPINK9-20-OR | 20 (40 μL) | 200 μL |  |
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| SPINK9-20-GO | 20 (40 μL) | 200 μL |  |
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| SPINK9-20-GR | 20 (40 μL) | 200 μL |  |
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| SPINK9-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a Kazal-type serine protease inhibitor that appears to specifically target kallikrein-related peptidase 5 (KLK5) in the palmo-plantar epidermis. KLK5 is an important initiator of skin desquamation, so the encoded protease inhibitor may regulate skin differentiation in the palms of hands and soles of feet. This cationic protein has also been shown to promote keratinocyte migration by activation of the epidermal growth factor receptor (EGFR). [provided by RefSeq, Dec 2015]
Gene Symbol : SPINK9
Gene Name : Serine peptidase inhibitor, Kazal type 9
Chromosome : CHR 5: 148,323,218-148,341,973
Locus : 5q32
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