This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SPINT2-20-RE | 20 (40 μL) | 200 μL |  |
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| SPINT2-20-OR | 20 (40 μL) | 200 μL |  |
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| SPINT2-20-GO | 20 (40 μL) | 200 μL |  |
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| SPINT2-20-GR | 20 (40 μL) | 200 μL |  |
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| SPINT2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Gene Symbol : SPINT2
Gene Name : Serine peptidase inhibitor, Kunitz type 2
Chromosome : CHR 19: 382,644,57-382,926,13
Locus : 19q13.2
Alt. Genes : AASS
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