This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SPOP-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| SPOP-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| SPOP-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| SPOP-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| SPOP-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
Gene Symbol : SPOP
Gene Name : Speckle type BTB/POZ protein
Chromosome : CHR 17: 496,781,62-495,988,83
Locus : 17q21.33
Alt. Genes : LRPPRC
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.